The Syrian American Medical Society (SAMS) reaffirmed its commitment to delivering free medical care, education, and urgent healthcare support in response to Syria's power transition that ended Assad-led governance. The organization outlined immediate priorities including emergency medical support, mental health care, and system support to address severe shortages and infrastructure challenges in crisis-affected regions.

On December 12, 2024, the Syrian American Medical Society (SAMS) announced a comprehensive plan to expand emergency healthcare services in response to the collapse of the Assad regime. The organization detailed actions including the deployment of ambulances, expansion of ICU capacities, activation of telemedicine programs, and support for mental health services, aiming to rebuild Syria’s healthcare system and uphold accountability for past atrocities.

SAMS has publicly called on the global community to reaffirm its commitment to humanitarian access, justice, and accountability. In its statement, the organization warns that current political moves toward reintegrating the Syrian regime into regional institutions and implementing forced repatriation schemes risk politicizing humanitarian aid and endangering vulnerable populations.

In 2023, a 60 Minutes report documented how the Syrian American Medical Society, alongside the White Helmets, mobilized volunteer medical and humanitarian aid in northwest Syria to support survivors in the aftermath of devastating earthquakes.

The article documents SAMS' extensive humanitarian initiatives, highlighting life-saving medical care provided in conflict-affected areas of Syria and neighboring countries. These efforts include emergency surgeries, chronic care, and infrastructure support in SAMS-backed hospitals, which directly aid vulnerable populations affected by authoritarian conflict.

The Syrian American Medical Society has deployed over 100 volunteer doctors and raised more than $97 million in aid to support medical services in Syria. The organization is building an underground hospital in a rebel-held area to safeguard medical operations from the relentless attacks by Bashar al Assad's regime.