On April 8, 2025, during a political rally in Vancouver, New Democrat leader Jagmeet Singh joined LifeLabs workers on the picket line as they demanded improved wages, benefits, and working conditions, highlighting ongoing labor grievances at LifeLabs.

On April 3, 2025, during a session at the Saskatchewan Legislature, LifeLabs was scrutinized for its political donations to both the Republican Party and the Saskatchewan Party. Critics highlighted that these contributions were part of a broader issue involving a $60 million lab contract that was extended without a competitive process, raising concerns about favoritism and ties to far‐right political elements.

During a Saskatchewan Legislature session, the NDP criticized LifeLabs for its political donations, including contributions to the Republican Party and over $30,000 to the Sask Party, while the province extended its $60 million lab contract without a competitive process. Critics argue that these donations may have influenced the awarding of a lucrative public healthcare contract.

Following mounting labor unrest and strike action led by unionized employees, LifeLabs has initiated rolling closures of its facilities starting Thursday. Critics argue this move punishes workers demanding fair treatment and improved conditions in a turbulent labor dispute.

LifeLabs faces a prolonged labor dispute as about 1,200 employees have been on rotating strikes since February 16, due to proposals including a 20% reduction in sick pay and substandard wages compared to hospital counterparts, which has raised serious labor rights concerns.

Workers at B.C. LifeLabs issued a 72-hour strike notice after months of negotiations ended with the company's refusal to adjust wages and benefits in line with the cost of living, highlighting significant labor rights concerns.

An Ontario court dismissed LifeLabs' four‐year legal battle to block the release of a report on a 2019 data breach that compromised millions of Canadians' health data. The report found that LifeLabs failed to take reasonable steps to protect patient information, and the company's legal attempts to delay transparency have raised serious concerns about its commitment to ethical business practices and public accountability.

An investigation report published after a 2019 cyberattack revealed that LifeLabs failed to safeguard the personal and health information of millions of Canadians as required by provincial privacy laws. The company also attempted to block the public release of the report by invoking solicitor-client privilege, a move that undermined transparency and public accountability.

LifeLabs and its unionized workers reached a tentative three-year contract agreement, averting further job action after the union initiated an overtime ban and work-to-rule campaign.

An investigation by CTV News revealed that LifeLabs failed to protect the personal health information of millions of Canadians, highlighting a significant lapse in ethical responsibility regarding data protection.

LifeLabs has, since 2016, donated approximately $30,000 to the Saskatchewan Party, coinciding with the company securing a government contract worth over $60 million in laboratory services in Regina and Saskatoon. Critics argue that such donations may have influenced contract awards, raising concerns about the intersection of corporate contributions and public procurement, especially given LifeLabs' ties to a U.S.-based company known for supporting right-wing political causes.